Multivesicular Assemblies as Real-World Testbeds for Embryogenic Evolutionary Systems

  • Authors:
  • Maik Hadorn;Peter Eggenberger Hotz

  • Affiliations:
  • Department of Informatics, Artificial Intelligence Laboratory, University of Zurich, Zurich, Switzerland 8050;The Mærsk Mc-Kinney Møller Institute, University of Southern Denmark, Odense M, Denmark 5230

  • Venue:
  • ACAL '09 Proceedings of the 4th Australian Conference on Artificial Life: Borrowing from Biology
  • Year:
  • 2009

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Abstract

Embryogenic evolution emulates in silico cell-like entities to get more powerful methods for complex evolutionary tasks. As simulations have to abstract from the biological model, implicit information hidden in its physics is lost. Here, we propose to use cell-like entities as a real-world in vitro testbed. In analogy to evolutionary robotics, where solutions evolved in simulations may be tested in real-world on macroscale, the proposed vesicular testbed would do the same for the embryogenic evolutionary tasks on mesoscale. As a first step towards a vesicular testbed emulating growth, cell division, and cell differentiation, we present a modified vesicle production method, providing custom-tailored chemical cargo, and present a novel self-assembly procedure to provide vesicle aggregates of programmable composition.