Automated Identification of Protein Structural Features

Authors:
Chandrasekhar Mamidipally;Santosh B. Noronha;Sumantra Dutta Roy
Affiliations:
Dept. of Chemical Engg., IIT Bombay, Powai, Mumbai, India 400 076;Dept. of Chemical Engg., IIT Bombay, Powai, Mumbai, India 400 076;Dept. of Electrical Engg., IIT Delhi, Hauz Khas, New Delhi, India 110 016
Venue:
PReMI '09 Proceedings of the 3rd International Conference on Pattern Recognition and Machine Intelligence
Year:
2009

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Abstract

This paper proposes an iterative clustering procedure for finding protein motifs which do not necessarily correspond to secondary structures, or to features along the protein backbone. We show the applicability of our method to two important applications namely, protein structure matching, and automatically identifying active sites and other biologically significant sub-structures in proteins.