CT image construction of the lung in a totally deflated mode

  • Authors:

  • Ali Sadeghi Naini;Rajni V. Patel;Abbas Samani

  • Affiliations:

  • Dept. of Electrical and Comp. Eng., The Univ. of Western Ontario, London, Ontario, Canada and Imaging Res. Laboratories, Robarts Res. Institute, London, Ontario, Canada and Canadian Surgical Techn ...;Dept. of Electrical and Comp. Eng., The Univ. of Western Ontario, London, Ontario, Canada and Imaging Res. Laboratories, Robarts Res. Institute, London, Ontario, Canada and Canadian Surgical Techn ...;Dept. of Electrical and Computer Engineering, The Univ. of Western Ontario, London, Ontario, Canada and Imaging Research Laboratories, Robarts Research Institute, London, Ontario, Canada and Depar ...

  • Venue:
  • ISBI'09 Proceedings of the Sixth IEEE international conference on Symposium on Biomedical Imaging: From Nano to Macro
  • Year:
  • 2009

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Abstract

A novel technique is proposed to construct CT images of the lung in a totally deflated mode using non-rigid registration and extrapolation. This CT image would be very useful in performing tumor ablative procedures (such as brachytherapy) for the treatment of lung cancer. This is because during such procedures the target lung is almost completely deflated whereas preoperative images are acquired while the lung is partially inflated. This makes pre-operative images very inaccurate. Given that Ultrasound (US) imaging is very sensitive to residual air in a deflated lung, it is not an effective intra-operative imaging modality by itself. One possible approach for image guided lung brachytherapy is registering low quality intra-operative ultrasound images to high quality lung CT image of the deflated lung constructed using the proposed technique. The technique was applied to an ex-vivo porcine lung and the preliminary results were found to be very encouraging.