Reproducibility of image-based computational hemodynamics in intracranial aneurysms: comparison of CTA and 3DRA

  • Authors:

  • A. J. Geers;I. Larrabide;A. G. Radaelli;H. Bogunovic;H. A. F. Gratama van Andel;C. B. Majoie;A. . Frangi

  • Affiliations:

  • Center for Computational Imaging and Simulation Technologies in Biomedicine, Universitat Pompeu Fabra and Networking Center on Biomedical Research;Networking Center on Biomedical Research and Center for Computational Imaging and Simulation Technologies in Biomedicine, Universitat Pompeu Fabra;Center for Computational Imaging and Simulation Technologies in Biomedicine, Universitat Pompeu Fabra and Networking Center on Biomedical Research;Center for Computational Imaging and Simulation Technologies in Biomedicine, Universitat Pompeu Fabra and Networking Center on Biomedical Research;Dept. of Biomedical Engineering & Physics, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands;Dept. of Radiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands;Center for Computational Imaging and Simulation Technologies in Biomedicine, Universitat Pompeu Fabra and Networking Center on Biomedical Research and Institució Catalana de Recerca i Estudis ...

  • Venue:
  • ISBI'09 Proceedings of the Sixth IEEE international conference on Symposium on Biomedical Imaging: From Nano to Macro
  • Year:
  • 2009

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Abstract

Hemodynamics play an important role in the pathogenesis of intracranial aneurysms and are believed to provide valuable information to predict aneurysmal rupture. Using image-based vascular models and computational fluid dynamics (CFD) techniques, the inter-aneurysmal hemodynamics can be studied in depth. In this paper, the effect of using different image-modalities is evaluated by investigating 4 middle cerebral arteries bifurcation aneurysms imaged with threedimensional rotational angiography (3DRA) and computed tomographic angiography (CTA). The presented visualizations show that the main flow characteristics are preserved. However, there are large discrepancies in quantitative measurements.