MICCAI'07 Proceedings of the 10th international conference on Medical image computing and computer-assisted intervention
Particle filtering for nonlinear BOLD signal analysis
MICCAI'06 Proceedings of the 9th international conference on Medical Image Computing and Computer-Assisted Intervention - Volume Part II
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The amplitude of the BOLD signal depends heavily upon the resting blood volume fraction (V0). However, most existing haemodynamic data assimilation studies pretermit such concern through assigning arbitrarily the value in a physiological plausible range. In this work, we presented the first exploration of the influence of the fraction V0 to model estimation, where the exact value of V0 was calibrated by MR angiography experiment. Our results show this process may greatly increase the accuracy of the data assimilation procedure. Furthermore, they also suggest that the result of traditional intensity-based activation inference would displace spatially from the realistic activated locus, the estimated neuronal efficiency parameter Ɛ can accurately label the activated region, thus is a better candidate to evaluate activation level.