Nonlinear model for ECG R-R interval variation using genetic programming approach

  • Authors:
  • Yun Seok Chang;Kwang Suk Park;Bo Yeon Kim

  • Affiliations:
  • Department of Computer Engineering, Daejin University, Pocheon, Republic of Korea;Department of Biomedical Engineering, College of Medicine, Seoul National University, Seoul, Republic of Korea;Department of Electrical and Computer Engineering, Kangwon National University, Chuncheon, Republic of Korea

  • Venue:
  • Future Generation Computer Systems
  • Year:
  • 2005

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Abstract

This paper proposes a nonlinear system modeling method, which predicts characteristics of the ECG R-R interval variation. For determining model equation, we adopted a genetic programming method in which the chromosome represents the model equation consisting of time-delayed variables, constants, and four arithmetic operators, and determines the fitness function. By genetic programming, sequences of regressive nonlinear equations are produced and evolved until the finding of the optimal model equation, which could simulate the spectral, statistical and nonlinear behavior of the given R-R interval dynamics. Experimental results showed that the evolutionary approach could find the equation which simulates the spectral and chaotic dynamics of the given signal. Therefore, the proposed evolutionary approach is useful for the system identification of the nonlinear biological system.