Probabilistic reasoning in intelligent systems: networks of plausible inference
Probabilistic reasoning in intelligent systems: networks of plausible inference
Information Retrieval
Dynamic bayesian networks: representation, inference and learning
Dynamic bayesian networks: representation, inference and learning
Journal of Cognitive Neuroscience
Spatially organized spike correlation in cat visual cortex
Neurocomputing
Measure of correlation orthogonal to change in firing rate
Neural Computation
Learning bayesian network structure from massive datasets: the «sparse candidate« algorithm
UAI'99 Proceedings of the Fifteenth conference on Uncertainty in artificial intelligence
Large-sample learning of bayesian networks is NP-hard
UAI'03 Proceedings of the Nineteenth conference on Uncertainty in Artificial Intelligence
Methodological Review: A review of causal inference for biomedical informatics
Journal of Biomedical Informatics
Mimicking human neuronal pathways in silico: an emergent model on the effective connectivity
Journal of Computational Neuroscience
An overview of bayesian methods for neural spike train analysis
Computational Intelligence and Neuroscience - Special issue on Modeling and Analysis of Neural Spike Trains
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Coordination among cortical neurons is believed to be a key element in mediating many high-level cortical processes such as perception, attention, learning, and memory formation. Inferring the structure of the neural circuitry underlying this coordination is important to characterize the highly nonlinear, time-varying interactions between cortical neurons in the presence of complex stimuli. In this work, we investigate the applicability of dynamic Bayesian networks (DBNs) in inferring the effective connectivity between spiking cortical neurons from their observed spike trains. We demonstrate that DBNs can infer the underlying nonlinear and time-varying causal interactions between these neurons and can discriminate between mono-and polysynaptic links between them under certain constraints governing their putative connectivity. We analyzed conditionally Poisson spike train data mimicking spiking activity of cortical networks of small and moderately large size. The performance was assessed and compared to other methods under systematic variations of the network structure to mimic a wide range of responses typically observed in the cortex. Results demonstrate the utility of DBN in inferring the effective connectivity in cortical networks.