Nonlinear component analysis as a kernel eigenvalue problem
Neural Computation
A Tutorial on Support Vector Machines for Pattern Recognition
Data Mining and Knowledge Discovery
Reducing multiclass to binary: a unifying approach for margin classifiers
The Journal of Machine Learning Research
Multivariate image analysis in biomedicine
Journal of Biomedical Informatics
Multiclass cell detection in bright field images of cell mixtures with ECOC probability estimation
Image and Vision Computing
Solving multiclass learning problems via error-correcting output codes
Journal of Artificial Intelligence Research
Computers in Biology and Medicine
A new preprocessing approach for cell recognition
IEEE Transactions on Information Technology in Biomedicine
Object type recognition for automated analysis of protein subcellular location
IEEE Transactions on Image Processing
An introduction to kernel-based learning algorithms
IEEE Transactions on Neural Networks
Multimodal Information Integration and Fusion for Histology Image Classification
International Journal of Multimedia Data Engineering & Management
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In this paper, we describe a framework for multiclass cell detection in composite images consisting of images obtained with three different contrast methods for transmitted light illumination (referred to as multicontrast composite images). Compared to previous multiclass cell detection results [1], the use of multicontrast composite images was found to improve the detection accuracy by introducing more discriminatory information into the system. Preprocessing multicontrast composite images with Kernel PCA was found to be superior to traditional linear PCA preprocessing, especially in difficult classification scenarios where high-order nonlinear correlations are expected to be important. Systematic study of our approach under different overlap conditions suggests that it possesses sufficient speed and accuracy for use in some practical systems.