Experimental validation of a radiographic simulation code using breast phantom for X-ray imaging

  • Authors:

  • K. Bliznakova;R. Speller;J. Horrocks;P. Liaparinos;Z. Kolitsi;N. Pallikarakis

  • Affiliations:

  • Department of Medical Physics, Faculty of Medicine, University of Patras, 26500 Rio, Patras, Greece;Department of Medical Physics and Bioengineering, University College London, London, UK;Clinical Physics Group, St Bartholomew's Hospital, London, UK;Department of Medical Instruments Technology, Technological Educational Institute of Athens, Athens, Greece;Department of Medical Physics, Faculty of Medicine, University of Patras, 26500 Rio, Patras, Greece;Department of Medical Physics, Faculty of Medicine, University of Patras, 26500 Rio, Patras, Greece

  • Venue:
  • Computers in Biology and Medicine
  • Year:
  • 2010

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Abstract

Computer models and simulations of X-ray imaging systems are becoming a very precious tool during the development and evaluation of new X-ray imaging techniques. To provide, however, a faithful simulation of a system, all components must be accurately modelled and tested, followed by verification through experimental measurements. This paper presents a validation study of the XRayImagingSimulator, an in-house developed X-ray imaging simulator, which is extensively used as a basic tool in carrying out complex breast imaging simulations. The approach followed compares results obtained via an experimental setup for breast phantom (CIRS 011A) imaging, using synchrotron radiation (SYRMEP beamline at ELETTRA), with those from its simulated setup under the same conditions. The study demonstrated a very good agreement between experimental and simulated images compared both in terms of subjective and objective criteria. The combination of the XRayImagingSimulator with our BreastSimulator provides a powerful tool for in silico testing of new X-ray breast imaging approaches.