Spike-timing dependent plasticity as a mechanism for ocular dominance shift

  • Authors:

  • Beth Ann Siegler;Maureen Ritchey;Jonathan Rubin

  • Affiliations:

  • Center for Neuroscience, University of Pittsburgh, Pittsburgh, PA 15260, USA;University of Notre Dame, South Bend, IN 46556, USA;Department of Mathematics and Center for the Neural Basis of Cognition, University of Pittsburgh, Pittsburgh, PA 15260, USA

  • Venue:
  • Neurocomputing
  • Year:
  • 2005

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Abstract

Spike-timing dependent plasticity (STDP) has been implicated in visual cortex modification. We created a model of ocular dominance (OD) shift based on STDP rules and compared it to experimental results. Although STDP proved to be a powerful mechanism for OD shift in our model, we found that it was unable to account for more subtle effects of monocular deprivation.