A spike sorting framework using nonparametric detection and incremental clustering

  • Authors:
  • Mingzhou (Joe) Song;Hongbin Wang

  • Affiliations:
  • Department of Computer Science, New Mexico State University, Las Cruces, NM 88003, USA;Doctoral Program in Computer Science, Graduate Center, City University of New York, NY 10016, USA

  • Venue:
  • Neurocomputing
  • Year:
  • 2006

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Abstract

We introduce a statistical computing framework to address two important issues in spike sorting: flexible spike shape modeling and realtime spike clustering. In this framework, spikes are detected based on a nonparametric shape distribution; detected spikes are further grouped by an incremental clustering algorithm involving the second-order statistics-covariance matrix. We performed experiments on both simulated and real signals to study spike detection accuracy and cluster separation.