A Theory for Multiresolution Signal Decomposition: The Wavelet Representation
IEEE Transactions on Pattern Analysis and Machine Intelligence
Neural Networks
Tissue classification with gene expression profiles
RECOMB '00 Proceedings of the fourth annual international conference on Computational molecular biology
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CBMS '02 Proceedings of the 15th IEEE Symposium on Computer-Based Medical Systems (CBMS'02)
Artificial Intelligence Review
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IEEE Transactions on Systems, Man, and Cybernetics, Part B: Cybernetics
Entropy-based algorithms for best basis selection
IEEE Transactions on Information Theory - Part 2
IEEE Transactions on Image Processing
IEEE Transactions on Information Technology in Biomedicine - Special section on biomedical informatics
Computers in Biology and Medicine
Colon cancer prediction with genetics profiles using evolutionary techniques
Expert Systems with Applications: An International Journal
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Expert Systems with Applications: An International Journal
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Knowledge-Based Systems
An automatic computer-aided diagnosis system for liver tumours on computed tomography images
Computers and Electrical Engineering
Computer Methods and Programs in Biomedicine
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In this paper, we propose the joint use of discrete wavelet transform (DWT)-based feature extraction and probabilistic neural network (PNN) classifier to classify tissues using gene expression data. In the feature extraction module, gene expression data are firstly transformed into time-scale domain by DWT and then the reconstructed signals by using wavelet transform are reduced to a lower dimensional feature space. In the module of tissue classification, the outputs of the extractor are fed into a PNN classifier, and the class labels are given finally. Some test and comparison experiments have been made to evaluate the performance of the proposed classification scheme, using the features extracted with as well as without wavelet transform processing procedure. Correct rates of 92% and 98.7% in tumour vs. normal classification have been obtained using the proposed scheme on two well-known data sets: a colon cancer data set and a human lung carcinomas data set.