Analysis of myocardial motion and strain patterns using a cylindrical B-spline transformation model

  • Authors:
  • Raghavendra Chandrashekara;Raad H. Mohiaddin;Daniel Rueckert

  • Affiliations:
  • Department of Computing, Imperial College of Science, Technology and Medicine, London, UK;Royal Brompton and Harefield NHS Trust, London, UK;Department of Computing, Imperial College of Science, Technology and Medicine, London, UK

  • Venue:
  • IS4TM'03 Proceedings of the 2003 international conference on Surgery simulation and soft tissue modeling
  • Year:
  • 2003

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Abstract

We present a novel method for tracking the motion of the myocardium in tagged magnetic resonance (MR) images of the heart using a nonrigid registration algorithm based on a cylindrical free-form deformation (FFD) model and the optimization of a cost function based on normalized mutual information (NMI). The new aspect of our work is that we use a FFD defined in a cylindrical rather than a Cartesian coordinate system. This models more closely the geometry and motion of the left ventricle (LV). Validation results using a cardiac motion simulator and tagged MR data from 6 normal volunteers are also presented.