Patient-specific biomechanical model of the brain: application to Parkinson's disease procedure

Authors:
Olivier Clatz;Hervé Delingette;Eric Bardinet;Didier Dormont;Nicholas Ayache
Affiliations:
INRIA Sophia Antipolis, Sophia Antipolis, France;INRIA Sophia Antipolis, Sophia Antipolis, France;INRIA Sophia Antipolis, Sophia Antipolis, France and Neuroradiology Dept and LENA UPR 640-CNRS La Pitié-Salpêtriére hospital, Paris, France;Neuroradiology Dept and LENA UPR-CNRS La Pitié-Salpêtriére hospital, Paris, France;INRIA Sophia Antipolis, Sophia Antipolis, France
Venue:
IS4TM'03 Proceedings of the 2003 international conference on Surgery simulation and soft tissue modeling
Year:
2003

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Abstract

Stereotactic neurosurgery for Parkinson's disease consists of stimulating deep nuclei of the brain. Although target coordinates are calculated with high precision on the pre-operative images, cerebrospinal fluid (CSF) leakage during the procedure can lead to a brain deformation and cause potential error with respect to the surgical planning. In this paper, we propose a patient-specific biomechanical model of the brain able to recover the global deformation of the brain during this type of neurosurgical procedure. Such a model could be used to update the pre-operative planning and balance the mechanical effects of the intraoperative brain shift.