Integrating mutations data of the TP53 human gene in the bioinformatics network environment

Authors:
Domenico Marra;Paolo Romano
Affiliations:
Bioinformatics and Structural Proteomics, National Cancer Research Institute, Genova, Italy;Bioinformatics and Structural Proteomics, National Cancer Research Institute, Genova, Italy
Venue:
BIRD'07 Proceedings of the 1st international conference on Bioinformatics research and development
Year:
2007

Citing 1
Cited 0

Taverna: a tool for the composition and enactment of bioinformatics workflows

Bioinformatics

Quantified Score

Hi-index	0.00

Visualization

Abstract

We present in this paper some new network tools that can improve the accessibility of information on mutations of the TP53 human gene with the aims of allowing for the integration of this data in the growing bioinformatics network environment and of demonstrating a possible methodology for biological data integration. We implemented the IARC TP53 Mutations Database and related subsets in an SRS site, set up some Web Services allowing for a software oriented, programmatic access to this data, created some demo workflows that illustrate how to interact with Web Services and implemented these workflows in the biowep (Workflow Enactment Portal for Bioinformatics) system. In conclusion, we discuss a new flexible and adaptable methodology for data integration in the biomedical research application domain.