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Kernel-based machine learning techniques, such as support vector machines, regularization networks, have been widely used in pattern analysis. Kernel function plays an important role in the design of such learning machines. The choice of an appropriate kernel is critical in order to obtain good performance. This paper presents a new class of kernel functions derived from framelet. Framelet is a wavelet frame constructed via multiresolution analysis, and has both the merit of frame and wavelet. The usefulness of the new kernels is demonstrated through simulation experiments.