Modeling the electrical activity of a neuron by a continuous and piecewise affine hybrid system

  • Authors:
  • Jean-Guillaume Dumas;Aude Rondepierre

  • Affiliations:
  • Laboratoire de Modélisation et Calcul, Grenoble cedex 9, France;Laboratoire de Modélisation et Calcul, Grenoble cedex 9, France

  • Venue:
  • HSCC'03 Proceedings of the 6th international conference on Hybrid systems: computation and control
  • Year:
  • 2003

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Abstract

A hybrid system is proposed to model the electrical potential emitted by a neuron as a response to an externally applied DC current. Experimentally, Hodgkin and Huxley built a four-dimensional and non-linear dynamical system to simulate this activity. Our idea is to use a new continuous and piecewise affine approximation as a hybrid model of the Hodgkin-Huxley dynamic. Our new model reproduces the Hodgkin-Huxley features with good accuracy (e.g. including the fact that the incoming current intensity is a bifurcation parameter), and, moreover, still allows an analytic computation of its solutions.