Modelling yeast pre-rRNA processing

  • Authors:

  • Federica Ciocchetta;Jane Hillston;Martin Kos;David Tollervey

  • Affiliations:

  • Laboratory for Foundations of Computer Science, The University of Edinburgh, Edinburgh, Scotland;Laboratory for Foundations of Computer Science, The University of Edinburgh, Edinburgh, Scotland;The Wellcome Trust Center for Cell Biology, The University of Edinburgh, Edinburgh, Scotland;The Wellcome Trust Center for Cell Biology, The University of Edinburgh, Edinburgh, Scotland

  • Venue:
  • CMSB'07 Proceedings of the 2007 international conference on Computational methods in systems biology
  • Year:
  • 2007

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Abstract

In this paper we present a quantified model concerning the synthesis of pre-rRNAs. The chemical kinetics simulation software Dizzy has been chosen as both the modelling and simulation framework of our study. We discuss the validation of the model against the available experimental data and we show some preliminary results obtained from the study of our model. All the analyses are based on stochastic simulation.