Soft level set coupling for LV segmentation in gated perfusion SPECT

Authors:
Timo Kohlberger;Gareth Funka-Lea;Vladimir Desh
Affiliations:
Siemens Corporate Research, Imaging and Visualization Department, Princeton, NJ;Siemens Corporate Research, Imaging and Visualization Department, Princeton, NJ;Siemens Corporate Research, Imaging and Visualization Department, Princeton, NJ
Venue:
MICCAI'07 Proceedings of the 10th international conference on Medical image computing and computer-assisted intervention - Volume Part I
Year:
2007

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Abstract

We present a new segmentation approach for the myocardium in gated and non-gated perfusion SPECT images. To this end, we represent the epi- and endocardiumby separate signed distance functions and couple them by a soft constraint to give explicit control over the wall thickness. By an explicit modeling of the basal plane, the volume of the blood pool as well as the myocardium are determinable. Furthermore, prior shape information is incorporated by applying a kernel density estimation on a number of expert segmentations in a low-dimensional PCA subspace. Thereby, information along the time axis is fully taken into account by employing 4-dimensional embedding functions.