Mining biosignal data: coronary artery disease diagnosis using linear and nonlinear features of HRV

Authors:
Heon Gyu Lee;Ki Yong Noh;Keun Ho Ryu
Affiliations:
Database/Bioinformatics Laboratory, School of Electrical & Computer Engineering, Chungbuk National University, Cheongju, Korea;Korea Research Institutes of Standards and Science, Korea;Database/Bioinformatics Laboratory, School of Electrical & Computer Engineering, Chungbuk National University, Cheongju, Korea
Venue:
PAKDD'07 Proceedings of the 2007 international conference on Emerging technologies in knowledge discovery and data mining
Year:
2007

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Abstract

The main purpose of our study is to propose a novel methodology to develop the multi-parametric feature including linear and nonlinear features of HRV (Heart Rate Variability) diagnosing cardiovascular disease. To develop the multi-parametric feature of HRV, we used the statistical and classification techniques. This study analyzes the linear and the non-linear properties of HRV for three recumbent positions, namely the supine, left lateral and right lateral position. Interaction effect between recumbent positions and groups (normal and patients) was observed based on the HRV indices and the extracted HRV indices used to classify the CAD (Coronary Artery Disease) group from the normal people. We have carried out various experiments on linear and non-linear features of HRV indices to evaluate several classifiers, e.g., Bayesian classifiers, CMAR, C4.5 and SVM. In our experiments, SVM outperformed the other classifiers.