A novel two sources ultrasound modulated optical tomographic system for screening breast cancer through elasticity characterization

  • Authors:
  • M. Suheshkumar Singh;K. Rajan;R. M. Vasu;K. Sijeesh

  • Affiliations:
  • Department of Physics, Indian Institute of Science, Bangalore, India;Department of Physics, Indian Institute of Science, Bangalore, India;Department of Instrumentation, Indian Institute of Science, Bangalore, India;Department of Instrumentation, Indian Institute of Science, Bangalore, India

  • Venue:
  • ICIP'09 Proceedings of the 16th IEEE international conference on Image processing
  • Year:
  • 2009

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Abstract

The study of non-invasive characterization of elastic properties of soft biological tissues has been a focus of active researches since recent years. Light is highly scattered by biological tissues and hence, sophisticated reconstruction algorithms are required to achieve good imaging depth and a reasonable resolution. Ultrasound (US), on the otherhand, is less scattered by soft tissues and it has been in use for imaging in biomedical ultrasound systems. Combination of the contrast sensitivity of light and good localization of ultrasound provides a challenging technique for characterization of thicker tissues deep inside the body non-invasively. The elasticity of the tissues is characterized by studying the response of tissues to mechanical excitation induced by an acoustic radiation force (remotely) using an optical laser. The US modulated optical signals which traverse the tissue are detected by using a CCD camera as detector array and the pixel map formed on the CCD is used to characterize the embedded inhomogeneities. The use of CCD camera improves the signal-noiseratio (SNR) by averaging the signals from all of the CCD pixels.