Computing with words with the ontological self-organizing map

Authors:
Timothy C. Havens;James M. Keller;Mihail Popescu
Affiliations:
Department of Electrical and Computer Engineering, University of Missouri, Columbia, MO;Department of Electrical and Computer Engineering, University of Missouri, Columbia, MO;Department of Health Management and Informatics, University of Missouri, Columbia, MO
Venue:
IEEE Transactions on Fuzzy Systems - Special section on computing with words
Year:
2010

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Abstract

This paper addresses the computing-with-words paradigm by presenting an ontological self-organizing map (OSOM), which produces visualization and summarization information about datasets composed of words, namely, ontological data. The specific data that are used in this paper are the Gene Ontology (GO) annotations of genes and gene products. The OSOM is an extension of the SOM, which was initially developed by Kohonen. We adapt the SOM by integrating ontology-based similarity measures and relational-clustering distance measures. We also develop a novel prototype update. We present results on two datasets composed of GO annotations of genes and gene products. An OSOM-based summarization, which produces the term-based summarizations of the trained OSOM network, is also demonstrated. The results show that the OSOM-based visualization method correctly shows the cluster tendency of the genes and gene products and that the summarization provides useful information about the mapped groups of genes and gene products.