New algebraic constructions for pooling design in DNA library screening

  • Authors:

  • Zengti Li;Suogang Gao;Hongjie Du;Yan Shi;Weili Wu

  • Affiliations:

  • Mathematics and Information College, Langfang Normal College, Langfang 065000, China.;Mathematics and Information College, Hebei Normal University, Shijiazhuang 050016, China.;Department of Computer Science, University of Texas at Dallas, Richardson, Texas 75080, USA.;Department of Computer Science, University of Texas at Dallas, Richardson, Texas 75080, USA.;Department of Computer Science, University of Texas at Dallas, Richardson, Texas 75080, USA

  • Venue:
  • International Journal of Bioinformatics Research and Applications
  • Year:
  • 2010

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Abstract

Pooling design is an important mathematical tool in DNA library screening. It has been showed that using pooling design, the number of tests in DNA library screening can be greatly reduced. In this paper, we present some new algebraic constructions for pooling design.