Spike sorting of muscle spindle afferent nerve activity recorded with thin-film intrafascicular electrodes

  • Authors:

  • Milan Djilas;Christine Azevedo-Coste;David Guiraud;Ken Yoshida

  • Affiliations:

  • Vision Institute, Paris, France;LIRMM/INRIA, University of Montpellier 2, Montpellier Cedex, France;LIRMM/INRIA, University of Montpellier 2, Montpellier Cedex, France;Biomedical Engineering Department, Indiana University-Purdue University Indianapolis, Indianapolis, IN and Center for Sensory-Motor Interaction, Department of Health Science and Technology, Aalbor ...

  • Venue:
  • Computational Intelligence and Neuroscience - Special issue on signal processing for neural spike trains
  • Year:
  • 2010

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Abstract

Afferent muscle spindle activity in response to passive muscle stretch was recorded in vivo using thin-film longitudinal intrafascicular electrodes. A neural spike detection and classification scheme was developed for the purpose of separating activity of primary and secondary muscle spindle afferents. The algorithm is based on the multiscale continuous wavelet transform using complex wavelets. The detection scheme outperforms the commonly used threshold detection, especially with recordings having low signal-to-noise ratio. Results of classification of units indicate that the developed classifier is able to isolate activity having linear relationship with muscle length, which is a step towards online model-based estimation of muscle length that can be used in a closed-loop functional electrical stimulation system with natural sensory feedback.