Partition-conditional ICA for Bayesian classification of microarray data

Authors:
Liwei Fan;Kim-Leng Poh;Peng Zhou
Affiliations:
Department of Industrial and Systems Engineering, National University of Singapore, 10 Kent Ridge Crescent, Singapore 119260, Singapore;Department of Industrial and Systems Engineering, National University of Singapore, 10 Kent Ridge Crescent, Singapore 119260, Singapore;College of Economics and Management, Nanjing University of Aeronautics and Astronautics, 29 Yudao Street, Nanjing 210016, PR China
Venue:
Expert Systems with Applications: An International Journal
Year:
2010

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Abstract

Accurate classification of microarray data is very important for medical decision making. Past studies have shown that class-conditional independent component analysis (CC-ICA) is capable of improving the performance of naive Bayes classifier in microarray data analysis. However, when a microarray dataset has a small number of samples for some classes, the application of CC-ICA may become infeasible. This paper extends CC-ICA and proposes a partition-conditional independent component analysis (PC-ICA) method for naive Bayes classification of microarray data. Compared to ICA and CC-ICA, PC-ICA represents an in-between concept for feature extraction. Our experimental results on two microarray datasets show that PC-ICA is more effective than ICA in improving the performance of naive Bayes classification of microarray data.