Gene symbol disambiguation using knowledge-based profiles
Bioinformatics
Species disambiguation for biomedical term identification
BioNLP '08 Proceedings of the Workshop on Current Trends in Biomedical Natural Language Processing
High-precision biological event extraction with a concept recognizer
BioNLP '09 Proceedings of the Workshop on Current Trends in Biomedical Natural Language Processing: Shared Task
TX task: automatic detection of focus organisms in biomedical publications
BioNLP '09 Proceedings of the Workshop on Current Trends in Biomedical Natural Language Processing
Combining multiple evidence for gene symbol disambiguation
BioNLP '07 Proceedings of the Workshop on BioNLP 2007: Biological, Translational, and Clinical Language Processing
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We introduce a system developed for the BioCreative II.5 community evaluation of information extraction of proteins and protein interactions. The paper focuses primarily on the gene normalization task of recognizing protein mentions in text and mapping them to the appropriate database identifiers based on contextual clues. We outline a "“fuzzy” dictionary lookup approach to protein mention detection that matches regularized text to similarly regularized dictionary entries. We describe several different strategies for gene normalization that focus on species or organism mentions in the text, both globally throughout the document and locally in the immediate vicinity of a protein mention, and present the results of experimentation with a series of system variations that explore the effectiveness of the various normalization strategies, as well as the role of external knowledge sources. While our system was neither the best nor the worst performing system in the evaluation, the gene normalization strategies show promise and the system affords the opportunity to explore some of the variables affecting performance on the BCII.5 tasks.