Ultrasonographic plaque characterization using a Rayleigh mixture model

  • Authors:
  • José Seabra;João Sanches;Franscesco Ciompi;Petia Radeva

  • Affiliations:
  • Institute for Systems and Robotics, Instituto Superior Técnico, Lisboa, Portugal;Institute for Systems and Robotics, Instituto Superior Técnico, Lisboa, Portugal;Computer Vision Center, Bellaterra, Barcelona, Spain;Computer Vision Center, Bellaterra, Barcelona, Spain

  • Venue:
  • ISBI'10 Proceedings of the 2010 IEEE international conference on Biomedical imaging: from nano to Macro
  • Year:
  • 2010

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Abstract

A correct modelling of tissue morphology is determinant for the identification of vulnerable plaques. This paper aims at describing the plaque composition by means of a Rayleigh Mixture Model applied to ultrasonic data. The effectiveness of using a mixture of distributions is established through synthetic and real ultrasonic data samples. Furthermore, the proposed mixture model is used in a plaque classification problem in Intravascular Ultrasound (IVUS) images of coronary plaques. A classifier tested on a set of 67 in-vitro plaques, yields an overall accuracy of 86% and sensitivity of 92%,94% and 82%, for fibrotic, calcified and lipidic tissues, respectively. These results strongly suggest that different plaques types can be distinguished by means of the coefficients and Rayleigh parameters of the mixture distribution.