Detecting mutually-salient landmark pairs with MRF regularization

  • Authors:
  • Y. Ou;A. Besbes;M. Bilello;M. Mansour;C. Davatzikos;N. Paragios

  • Affiliations:
  • Section of Biomedical Image Analysis, Dept. of Radiology, Univ, of Pennsylvania;Laboratoire MAS, Ecole Centrale Paris, Châtenay-Malabry, France and Equipe GALEN, INRIA Saclay-Île-de-France, Orsay, France;Dept. of Radiology, Univ, of Pennsylvania;Dept. of Radiology, Univ, of Pennsylvania;Section of Biomedical Image Analysis, Dept. of Radiology, Univ, of Pennsylvania;Laboratoire MAS, Ecole Centrale Paris, Châtenay-Malabry, France and Equipe GALEN, INRIA Saclay-Île-de-France, Orsay, France

  • Venue:
  • ISBI'10 Proceedings of the 2010 IEEE international conference on Biomedical imaging: from nano to Macro
  • Year:
  • 2010

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Abstract

In this paper, we present a framework for extracting mutually-salient landmark pairs for registration. Traditional methods detect landmarks one-by-one and separately in two images. Therefore, the detected landmarks might inherit low discriminability and are not necessarily good for matching. In contrast, our method detects landmarks pair-by-pair across images, and those pairs are required to be mutually-salient, i.e., uniquely corresponding to each other. The second merit of our framework is that, instead of finding individually optimal correspondence, which is a local approach and could cause self-intersection of the resultant deformation, our framework adopts a Markov-random-field (MRF)-based spatial arrangement to select the globally optimal landmark pairs. In this way, the geometric consistency of the correspondences is maintained and the resultant deformations are relatively smooth and topology-preserving. Promising experimental validation through a radiologist's evaluation of the established correspondences is presented.