3D Image Analysis and Artificial Intelligence for Bone Disease Classification

  • Authors:
  • Abdurrahim Akgundogdu;Rachid Jennane;Gabriel Aufort;Claude Laurent Benhamou;Osman Nuri Ucan

  • Affiliations:
  • Department of Electrical and Electronics Eng, Istanbul University, Avcilar, Turkey 34850;Instiut PRISME / LESI, University of Orleans, Orléans Cedex 2, France 45067;Instiut PRISME / LESI, University of Orleans, Orléans Cedex 2, France 45067;Equipe INSERM U658, Hospital of Orleans, Orléans, France 45000;Department of Electrical and Electronics Eng, Istanbul University, Avcilar, Turkey 34850

  • Venue:
  • Journal of Medical Systems
  • Year:
  • 2010

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Abstract

In order to prevent bone fractures due to disease and ageing of the population, and to detect problems while still in their early stages, 3D bone micro architecture needs to be investigated and characterized. Here, we have developed various image processing and simulation techniques to investigate bone micro architecture and its mechanical stiffness. We have evaluated morphological, topological and mechanical bone features using artificial intelligence methods. A clinical study is carried out on two populations of arthritic and osteoporotic bone samples. The performances of Adaptive Neuro Fuzzy Inference System (ANFIS), Support Vector Machines (SVM) and Genetic Algorithm (GA) in classifying the different samples have been compared. Results show that the best separation success (100 %) is achieved with Genetic Algorithm.