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RSCTC'2010 Discovery Challenge was a special event of Rough Sets and Current Trends in Computing conference. The challenge was organized in the form of an interactive on-line competition, at TUNEDIT.org platform, in days between Dec 1, 2009 and Feb 28, 2010. The task was related to feature selection in analysis of DNA microarray data and classification of samples for the purpose of medical diagnosis or treatment. Prizes were awarded to the best solutions. This paper describes organization of the competition and the winning solutions.