Temporal abstraction in intelligent clinical data analysis: A survey
Artificial Intelligence in Medicine
Grand challenges in clinical decision support
Journal of Biomedical Informatics
Real-Time Service-Oriented Architectures to Support Remote Critical Care: Trends and Challenges
COMPSAC '08 Proceedings of the 2008 32nd Annual IEEE International Computer Software and Applications Conference
Creating and sharing clinical decision support content with Web 2.0: Issues and examples
Journal of Biomedical Informatics
Editorial: Lessons learnt from bringing knowledge-based decision support into routine use
Artificial Intelligence in Medicine
CIS system hazards derived from literature using systems and human factors perspectives
Proceedings of the 2nd ACM SIGHIT International Health Informatics Symposium
Automatic optimization of stream programs via source program operator graph transformations
Distributed and Parallel Databases
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We present a framework to model and translate clinical rules to support complex real-time analysis of both synchronous physiological data and asynchronous clinical data. The framework is demonstrated through a case study in a neonatal intensive care context showing how a clinical rule for detecting an apnoeic event is modeled across multiple physiological data streams in the Artemis environment, which employs IBM's InfoSphere Streams middleware to support real-time stream processing. Initial clinical hypotheses for apnoea detection are modeled using UML activity diagrams which are subsequently translated into Stream's SPADE code to be deployed in Artemis to deliver real-time decision support. Our aim is to provide a Clinical Decision Support System capable of identifying and detecting patterns in physiological data streams indicative of the onset of clinically significant conditions that that may adversely affect health outcomes. Benefits associated with our approach include: 1) reduced time and effort on the clinician's part to assess health data from multiple sources; 2) the ability to allow clinicians to control the rules-engine of Artemis to enhance clinical care within their unique environments; 3) the ability to apply clinical alerts to both synchronous and asynchronous data; and 4) the ability to continuously process data in real-time.