Retrieving samples from biobanks

  • Authors:
  • Claus Dabringer;Johann Eder

  • Affiliations:
  • Alps Adria University Klagenfurt, Department of Informatics Systems;Alps Adria University Klagenfurt, Department of Informatics Systems

  • Venue:
  • ITBAM'10 Proceedings of the First international conference on Information technology in bio- and medical informatics
  • Year:
  • 2010

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Abstract

Biobanks are extremely important resources for medical research: they collect biological material (samples) and data describing this material. Biobanks provide medical researchers with material and data they need for their studies. Data availability varies greatly among samples and makes the retrieval of data and identification of relevant samples a strenuous task. We show the challenges and limitations when using pure SQL statements for querying a relational database. To tackle the problem of locating interesting material we present a novel approach which automatically generates approximate queries with ranking capabilities. Medical researchers use a Query By Example interface to specify desired attributes and restrictions and assign weights to them to influence the ranking function.