Generative programming: methods, tools, and applications
Generative programming: methods, tools, and applications
EMF: Eclipse Modeling Framework 2.0
EMF: Eclipse Modeling Framework 2.0
Phenomenological models of synaptic plasticity based on spike timing
Biological Cybernetics - Special Issue: Object Localization
Eclipse Modeling Project: A Domain-Specific Language (DSL) Toolkit
Eclipse Modeling Project: A Domain-Specific Language (DSL) Toolkit
Knowledge representation meets simulation to investigate memory problems after seizures
BI'11 Proceedings of the 2011 international conference on Brain informatics
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Biologically realistic modeling has been greatly facilitated by the development of neuro-simulators, and the development of simulatorindependent formats for model exchange is the subject of multiple initiatives. Neuronal systems need to be described at multiple levels of granularity, and compared to other such multi-level systems they also exhibit emergent properties, which are best described with computational and psychological terminology. The links between these levels are often neither clear in terms of concepts nor of the underlying mathematics. Given that modeling and simulation depends on explicit formal descriptions, we argue that rapid prototyping of model descriptions and their mutual relations will be a key to making progress here. Here we propose to adapt the paradigm of domain-specific modeling from software engineering. Using the popular Eclipse platform, we develop the modular and extensible NeuroBench1 model and showcase a toolchain for code generation, which can also support, mediate between, and complement ongoing initiatives. This may kick-start the development of a multiplicity of model descriptions, which eventually may lead to ontologically sound multi-level descriptions of neuronal systems capturing neuronal, computational, and even psychological and social phenomena.