Multiple latticed cellular automata: HIV dynamics in coupled lymph node and peripheral blood compartments

  • Authors:
  • S. Moonchai;Y. Lenbury;W. Triampo

  • Affiliations:
  • Dept of Mathematics, Faculty of Science, Chiangmai University, Thailand and Centre of Excellence in Mathematics, Perdo, Thailand;Dept of Mathematics, Faculty of Science, Mahidol University, Thailand and Centre of Excellence in Mathematics, Perdo, Thailand;R&D Group of Biological and Environmental Physics, Dept. of Physics, Faculty of Science, Mahidol Univ., Thailand and Center of Excellence for Vector and Vector-Borne Diseases, Mahidol Univ., T ...

  • Venue:
  • ACS'10 Proceedings of the 10th WSEAS international conference on Applied computer science
  • Year:
  • 2010

Quantified Score

Hi-index 0.00

Visualization

Abstract

Cellular automata simulation approach has become well known as a useful technique to investigate complex biomedical systems in situations where traditional methodologies are difficult or too costly to employ. So far, relatively simple cellular automata models have been proposed to simulate the dynamics of HIV infection in human. Most cellular automata models only considered viral proliferation in the lymph node. However, most clinical indications of AIDS progression are based on blood data, because these data are most easily obtained. Since viral population circulates between lymph node and plasma, viral load in the two compartments are important for the description of HIV infection dynamics. We present here cellular automata simulations of a two-compartment model of HIV proliferation with delay.