Massive particles for brain tractography

  • Authors:
  • Ramón Aranda;Mariano Rivera;Alonso Ramírez-Manzanares;Manzar Ashtari;James C. Gee

  • Affiliations:
  • Centro De Invertigación en Matemáticas, Guanajuato, Gto, México;Centro De Invertigación en Matemáticas, Guanajuato, Gto, México;Universidad de Guanajuato, Departemento de Matemáticas, Guanajuato, Gto, México;Diffusion Tensor Imaging and Brain Morphometry Lab, Childrens Hospital of Philadelphia, Philadelphia, PA;Penn Image Computing and Science Laboratory, Department of Radiology, University of Pennsylvania, Philadelphia, PA

  • Venue:
  • MICAI'10 Proceedings of the 9th Mexican international conference on Advances in artificial intelligence: Part I
  • Year:
  • 2010

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Abstract

We propose a method for estimating axonal fiber connectivity pathways (cerebral connectivity fibers) from Multi-Tensor Diffusion Magnetic Resonance Imaging (MTD-MRI). Our method uses multiple local orientation information provided by MTD-MRI for leading stochastic walks of particles. We perform stochastic walks on particles with mass which introduce inertia and gravitational forces that result in filtered trajectories. Afterwards, the fiber bunches are estimated with a clustering procedure based on terminal points that allows us to eliminate outliers. The method's performance is evaluated on MTD-MRI from realistic synthetic data, a diffusion phantom and demonstrated in real human brain data.