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The paper presents a study on the determinative factors in producing tuberculosis, the compliance of patients to treatment, the aspects arising from the lack of collaboration of these patients in the correct and complete treatment of the disease and the risks of abandoning the therapy. The study is a retrospective one. For collecting data, it have been used a questionnaire with pre-codified questions, based on the factors considered by WHO (World Health Organization) as being determinant in adherence to treatment of people affected with tuberculosis. The questionnaire with pre-codified questions has been applied to persons that have been registered as having tuberculosis in the county of Brasov, Romania, in 2007, being excluded from the study all the transfers, confutation of diagnostic, death and children. The dates of the study have been processed by the SPSS 13.0 program. The initial idea is now transposed in a web questionnaire which stores this information in a database for subsequent statistical preparation and analysis.