International Journal of Computers in Healthcare
A Multiclass Classification Tool Using Cloud Computing Architecture
ASONAM '12 Proceedings of the 2012 International Conference on Advances in Social Networks Analysis and Mining (ASONAM 2012)
| Hi-index | 3.84 |
Summary: Phenotypic Up-regulated Gene Support Vector Machine (PUGSVM) is a cancer Biomedical Informatics Grid (caBIG™) analytical tool for multiclass gene selection and classification. PUGSVM addresses the problem of imbalanced class separability, small sample size and high gene space dimensionality, where multiclass gene markers are defined by the union of one-versus-everyone phenotypic upregulated genes, and used by a well-matched one-versus-rest support vector machine. PUGSVM provides a simple yet more accurate strategy to identify statistically reproducible mechanistic marker genes for characterization of heterogeneous diseases. Availability: http://www.cbil.ece.vt.edu/caBIG-PUGSVM.htm. Contact: yuewang@vt.edu Supplementary information:Supplementary data are available at Bioinformatics online.