Eigenfaces vs. Fisherfaces: Recognition Using Class Specific Linear Projection
IEEE Transactions on Pattern Analysis and Machine Intelligence
A Tutorial on Support Vector Machines for Pattern Recognition
Data Mining and Knowledge Discovery
Classification of SPECT Images of Normal Subjects versus Images of Alzheimer's Disease Patients
MICCAI '01 Proceedings of the 4th International Conference on Medical Image Computing and Computer-Assisted Intervention
Journal of Cognitive Neuroscience
ICAPR'05 Proceedings of the Third international conference on Pattern Recognition and Image Analysis - Volume Part II
Distance metric learning as feature reduction technique for the Alzheimer's disease diagnosis
IWINAC'11 Proceedings of the 4th international conference on Interplay between natural and artificial computation: new challenges on bioinspired applications - Volume Part II
A quantitative study on acupuncture effects for fighting migraine using SPECT images
IWINAC'11 Proceedings of the 4th international conference on Interplay between natural and artificial computation: new challenges on bioinspired applications - Volume Part II
ICA-based automatic classification of PET images from ADNI database
ICONIP'11 Proceedings of the 18th international conference on Neural Information Processing - Volume Part I
Association rule-based feature selection method for Alzheimer's disease diagnosis
Expert Systems with Applications: An International Journal
Functional brain image classification using association rules defined over discriminant regions
Pattern Recognition Letters
On the empirical mode decomposition applied to the analysis of brain SPECT images
Expert Systems with Applications: An International Journal
Artificial Intelligence in Medicine
Expert Systems with Applications: An International Journal
Expert Systems with Applications: An International Journal
LVQ-SVM based CAD tool applied to structural MRI for the diagnosis of the Alzheimer's disease
Pattern Recognition Letters
An analysis of unit tests of a flight software product line
Science of Computer Programming
Hi-index | 0.02 |
In Alzheimer's disease (AD) diagnosis process, functional brain image modalities such as Single-Photon Emission Computed Tomography (SPECT) and Positron Emission Tomography (PET) have been widely used to guide the clinicians. However, the current evaluation of these images entails a succession of manual reorientations and visual interpretation steps, which attach in some way subjectivity to the diagnostic. In this work, a complete computer aided diagnosis (CAD) system for an automatic evaluation of the neuroimages is presented. Principal component analysis (PCA)-based methods are proposed as feature extraction techniques, enhanced by other linear approaches such as linear discriminant analysis (LDA) or the measure of the Fisher discriminant ratio (FDR) for feature selection. The final features allow to face up the so-called small sample size problem and subsequently they are used for the study of neural networks (NN) and support vector machine (SVM) classifiers. The combination of the presented methods achieved accuracy results of up to 96.7% and 89.52% for SPECT and PET images, respectively, which means a significant improvement over the results obtained by the classical voxels-as-features (VAF) reference approach.