A network of pyramidal neurons is sensitive to the timing of its excitatory inputs

  • Authors:
  • Santi Chillemi;Michele Barbi;Angelo Di Garbo

  • Affiliations:
  • Istituto di Biofisica CNR, Sezione di Pisa, Via G. Moruzzi 1, 56124 Pisa, Italy;Istituto di Biofisica CNR, Sezione di Pisa, Via G. Moruzzi 1, 56124 Pisa, Italy;Istituto di Biofisica CNR, Sezione di Pisa, Via G. Moruzzi 1, 56124 Pisa, Italy

  • Venue:
  • Neurocomputing
  • Year:
  • 2011

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Abstract

The transmission of excitatory inputs by a network of coupled pyramidal cells is investigated by means of numerical simulations. The pyramidal cell models are coupled by excitatory synapses and each one receives an excitatory pulse at a random time extracted from a Gaussian distribution. Moreover, each cell model is injected with a noisy current. It was found that the excitatory coupling promotes the transmission of the synaptic inputs on a time scale of a few ms.