Material properties estimation of layered soft tissue based on MR observation and iterative FE simulation

Authors:
Mitsunori Tada;Noritaka Nagai;Takashi Maeno
Affiliations:
Digital Human Research Center, National Institute of Advanced Industrial Science and Technology, Koto-ku, Tokyo, Japan and CREST, Japan Science and Technology Agency;Keio University;Keio University
Venue:
MICCAI'05 Proceedings of the 8th international conference on Medical image computing and computer-assisted intervention - Volume Part II
Year:
2005

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Abstract

In order to calculate deformation of soft tissue under arbitrary loading conditions, we have to take both non-linear material characteristics and subcutaneous structures into considerations. The estimation method of material properties presented in this paper accounts for these issues. It employs a compression test inside MRI in order to visualize deformation of hypodermic layered structure of living tissue, and an FE model of the compressed tissue in which non-linear material model is assigned. The FE analysis is iterated with updated material constant until the difference between the displacement field observed from MR images and calculated by FEM is minimized. The presented method has been applied to a 3-layered silicon rubber phantom. The results show the excellent performance of our method. The accuracy of the estimation is better than 15 %, and the reproducibility of the deformation is better than 0.4 mm even for an FE analysis with different boundary condition.