Pulsed magnetic field exposure induces lasting changes in neural network dynamics

  • Authors:

  • Robert Z. Stodilka;Julien Modolo;Frank S. Prato;John A. Robertson;Charles Cook;John Patrick;Anne Beuter;Alex W. Thomas;Alexandre Legros

  • Affiliations:

  • Imaging Program, Lawson Health Research Institute, Department of Medical Biophysics, University of Western Ontario, St. Joseph's Health Care, 268 Grosvenor Street, London, Ontario, Canada N6A 4V2;Imaging Program, Lawson Health Research Institute, Department of Medical Biophysics, University of Western Ontario, St. Joseph's Health Care, 268 Grosvenor Street, London, Ontario, Canada N6A 4V2;Imaging Program, Lawson Health Research Institute, Department of Medical Biophysics, University of Western Ontario, St. Joseph's Health Care, 268 Grosvenor Street, London, Ontario, Canada N6A 4V2;Imaging Program, Lawson Health Research Institute, Department of Medical Biophysics, University of Western Ontario, St. Joseph's Health Care, 268 Grosvenor Street, London, Ontario, Canada N6A 4V2;Department of Neuroscience, University of Lethbridge 4401 University Drive, Lethbridge, Alberta, Canada T1K 3M4;Imaging Program, Lawson Health Research Institute, Department of Medical Biophysics, University of Western Ontario, St. Joseph's Health Care, 268 Grosvenor Street, London, Ontario, Canada N6A 4V2;Bordeaux Polytechnic Institute, Pessac, France;Imaging Program, Lawson Health Research Institute, Department of Medical Biophysics, University of Western Ontario, St. Joseph's Health Care, 268 Grosvenor Street, London, Ontario, Canada N6A 4V2;Imaging Program, Lawson Health Research Institute, Department of Medical Biophysics, University of Western Ontario, St. Joseph's Health Care, 268 Grosvenor Street, London, Ontario, Canada N6A 4V2

  • Venue:
  • Neurocomputing
  • Year:
  • 2011

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Abstract

How extremely low frequency (ELF) electromagnetic fields (such as power line exposure) impacts brain activity is today an intense area of research. One challenge is to unveil transduction mechanisms allowing ELF to interact with brain tissue. Thus, we present a cortical network model receiving internal and external stimuli. Using frequency analysis, we study how these stimuli durably modulate network dynamics depending on exposure duration, stimuli properties and transduction mechanisms. Our results indicate that these stimuli induce different responses in the frequency domain. Ultimately, such models might be useful in evaluating power line exposure thresholds, and in developing innovative brain stimulation methods.