Trials on tissue contractility estimation from cardiac cine MRI using a biomechanical heart model

Authors:
R. Chabiniok;P. Moireau;P.-F. Lesault;A. Rahmouni;J.-F. Deux;D. Chapelle
Affiliations:
INRIA, MACS Team, Le Chesnay, France;INRIA, MACS Team, Le Chesnay, France;AP-HP Hôpital Henri Mondor, Université Paris-Est Créteil, France;AP-HP Hôpital Henri Mondor, Université Paris-Est Créteil, France;AP-HP Hôpital Henri Mondor, Université Paris-Est Créteil, France;INRIA, MACS Team, Le Chesnay, France
Venue:
FIMH'11 Proceedings of the 6th international conference on Functional imaging and modeling of the heart
Year:
2011

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Abstract

In this paper we apply specific data assimilation methods in order to estimate regional contractility parameters in a biomechanical heart model, using as measurements real Cine MR images obtained in an animal experiment. We assess the effectiveness of this estimation based on independent knowledge of the controlled infarcted condition, and on late enhancement images. Moreover, we show that the estimated contractility values can improve the model behavior in itself, and that they can serve as an indicator of the local heart function, namely, to assist medical diagnosis for the post-infarct detection of hypokinetic or akinetic regions in the myocardial tissue.