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In this paper, we describe the formative activities related to HPC applications and TeraGrid at Texas Southern University (TSU). TSU is an urban MSI (minority serving institution) and HBCU with a very small student body in STEM areas (7% of the undergraduate population). We have a vibrant and diverse faculty. Limited resources compound the challenges faced by the HPC community at TSU. We faced several difficulties as well as successes in the building of HPC access and its utilization at TSU.