Multi-class probabilistic atlas-based segmentation method in breast MRI

  • Authors:
  • Albert Gubern-Mérida;Michiel Kallenberg;Robert Martí;Nico Karssemeijer

  • Affiliations:
  • University of Girona, Spain;Radboud University Nijmegen Medical Centre, The Netherlands;University of Girona, Spain;Radboud University Nijmegen Medical Centre, The Netherlands

  • Venue:
  • IbPRIA'11 Proceedings of the 5th Iberian conference on Pattern recognition and image analysis
  • Year:
  • 2011

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Abstract

Organ localization is an important topic in medical imaging in aid of cancer treatment and diagnosis. An example are the pharmacokinetic model calibration methods based on a reference tissue, where a pectoral muscle delineation in breast MRI is needed to detect malignancy signs. Atlas-based segmentation has been proven to be powerful in brain MRI. This is the first attempt to apply an atlas-based approach to segment breast in T1 weighted MR images. The atlas consists of 5 structures (fatty and dense tissues, heart, lungs and pectoral muscle). It has been used in a Bayesian segmentation framework to delineate the mentioned structures. Global and local registration have been compared, where global registration showed the best results in terms of accuracy and speed. Overall, a Dice Similarity Coefficient value of 0.8 has been obtained which shows the validity of our approach to Breast MRI segmentation.