A computational assessment of a blood vessel's compliance: a procedure based on computed tomography coronary angiography

  • Authors:
  • Piotr Porwik;Maciej Sosnowski;Tomasz Wesolowski;Krzysztof Wrobel

  • Affiliations:
  • University of Silesia, Institute of Computer Science, Sosnowiec;Medical University of Silesia, Katowice, Poland;University of Silesia, Institute of Computer Science, Sosnowiec;University of Silesia, Institute of Computer Science, Sosnowiec

  • Venue:
  • HAIS'11 Proceedings of the 6th international conference on Hybrid artificial intelligent systems - Volume Part I
  • Year:
  • 2011

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Abstract

Cardiovascular mortality remains a leading health and social problem in many countries throughout the world. Therefore, it is obvious that current preventive measures include early detection of atherosclerosis process. Computed tomography (CT) is one of imaging modalities allowing for noninvasive detection of atherosclerotic lesion within coronary arteries in subjects with accumulation of risk factors (smoking, high lipids, hypertension, etc.). Functional analysis of coronary arteries is usually approached by means of invasive procedures. We aimed at finding solution for evaluation of another kind of functional analysis of coronary arteries, namely vessel's wall compliance by means of CT coronary angiography. On the basis of the CT images of the vessels over entire cardiac cycles, the internal area of the blood vessel is measured and its changes during various phases of heartbeat (systole, diastole) are calculated. If the vessel wall has been changed by atherosclerotic plaque, either calcified or non-calcified, then its compliance will be reduced due to its stiffness. Calculation of coronary artery compliance requires a series of measurements, which is unreliable and impractical for doing manually. The overall methodology proposed in this paper assists in the preparation of a medical diagnosis.