Meta-learning based optimization of metabolic pathway data-mining inference system

  • Authors:
  • Tomás V. Arredondo;Wladimir O. Ormazábal;Diego C. Candel;Werner Creixell

  • Affiliations:
  • Departamento de Electrónica, Universidad Técnica Federico Santa María, Valparaíso, Chile;Departamento de Electrónica, Universidad Técnica Federico Santa María, Valparaíso, Chile;Departamento de Informática, Universidad Técnica Federico Santa María, Valparaíso, Chile;Departamento de Electrónica, Universidad Técnica Federico Santa María, Valparaíso, Chile and CSIS, The University of Tokyo, Tokyo, Japan

  • Venue:
  • IEA/AIE'11 Proceedings of the 24th international conference on Industrial engineering and other applications of applied intelligent systems conference on Modern approaches in applied intelligence - Volume Part II
  • Year:
  • 2011

Quantified Score

Hi-index 0.00

Visualization

Abstract

This paper describes a novel meta-learning (MTL) based methodology used to optimize a neural network based inference system. The inference system being optimized is part of a bioinformatic application built to implement a systematic search scheme for the identification of genes which encode enzymes of metabolic pathways. Different MTL implementations are contrasted with manually optimized inference systems. The MTL based approach was found to be flexible and able to produce better results than manual optimization.