Pooling designs for clone library screening in the inhibitor complex model

  • Authors:
  • Fei-Huang Chang;Huilan Chang;Frank K. Hwang

  • Affiliations:
  • Department of Mathematics and Science, National Taiwan Normal University, Taipei County, ROC 24449;Department of Applied Mathematics, National Chiao Tung University, Hsinchu, ROC 300;Department of Applied Mathematics, National Chiao Tung University, Hsinchu, ROC 300

  • Venue:
  • Journal of Combinatorial Optimization
  • Year:
  • 2011

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Abstract

In this paper we introduce inhibitors into the complex model and we give a lower bound and an upper bound of tests in a nonadaptive pooling design for some inhibitor complex model. We propose a very efficient pooling design for the general inhibitor complex model and extend it to the error-tolerant case.