Principles of multivariate analysis: a user's perspective
Principles of multivariate analysis: a user's perspective
MICCAI '98 Proceedings of the First International Conference on Medical Image Computing and Computer-Assisted Intervention
Classification of SPECT Images of Normal Subjects versus Images of Alzheimer's Disease Patients
MICCAI '01 Proceedings of the 4th International Conference on Medical Image Computing and Computer-Assisted Intervention
Sequential weighted least squares algorithm for PET image reconstruction
Digital Signal Processing
Knowledge and Information Systems - Special Issue on Mining Low-Quality Data
Effective Emission Tomography Image Reconstruction Algorithms for SPECT Data
ICCS '08 Proceedings of the 8th international conference on Computational Science, Part I
Nearest neighbor pattern classification
IEEE Transactions on Information Theory
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This paper presents a computer-aided diagnosis technique for improving the accuracy of the early diagnosis of the Alzheimer type dementia. The first proposed methodology is based on the selection of those voxels which present a greater difference between Controls and Alzheimer type dementia patients. The mean value of the intensities of the selected voxels is used as features for different classifiers. The proposed methodology reaches an accuracy of 89% in the classification task. A second criterion is chosen to select voxels based on considering those which present not only greater overall difference between both modalities (Controls and Alzheimer) but also present lower dispersion. The classification accuracy using this second condition increases to 94%.