Distributed Job Scheduling on Computational Grids Using Multiple Simultaneous Requests
HPDC '02 Proceedings of the 11th IEEE International Symposium on High Performance Distributed Computing
Design and Evaluation of a Resource Selection Framework for Grid Applications
HPDC '02 Proceedings of the 11th IEEE International Symposium on High Performance Distributed Computing
High Performance Parametric Modeling with Nimrod/G: Killer Application for the Global Grid?
IPDPS '00 Proceedings of the 14th International Symposium on Parallel and Distributed Processing
Grid Information Services for Distributed Resource Sharing
HPDC '01 Proceedings of the 10th IEEE International Symposium on High Performance Distributed Computing
An Online Credential Repository for the Grid: MyProxy
HPDC '01 Proceedings of the 10th IEEE International Symposium on High Performance Distributed Computing
GENIUS: a simple and easy way to access computational and data grids
Future Generation Computer Systems - iGrid 2002
Heuristic scheduling for bag-of-tasks applications in combination with QoS in the computational grid
Future Generation Computer Systems - Special issue: Advanced grid technologies
An analytical model for multi-tier internet services and its applications
SIGMETRICS '05 Proceedings of the 2005 ACM SIGMETRICS international conference on Measurement and modeling of computer systems
CBMS '05 Proceedings of the 18th IEEE Symposium on Computer-Based Medical Systems
The Anatomy of the Grid: Enabling Scalable Virtual Organizations
International Journal of High Performance Computing Applications
A portal for grid-enabled physics
ACSW Frontiers '05 Proceedings of the 2005 Australasian workshop on Grid computing and e-research - Volume 44
The AppLeS Parameter Sweep Template: User-level middleware for the Grid\m{1}
Scientific Programming
Computers in Biology and Medicine
Application of grid computing to parameter sweeps and optimizations in molecular modeling
Future Generation Computer Systems
Stochastic modeling and quality evaluation of workflow systems based on QWF-Nets
ICCS'06 Proceedings of the 6th international conference on Computational Science - Volume Part III
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In silico (on the computer) oncology is a complex and multiscale combination of sciences and technologies that focuses on the study and modelling of biological mechanisms related to the phenomenon of cancer at all levels of biocomplexity. In silico oncology simulation models may be used for evaluating and comparing different therapeutic schemes, while at the same time considering different values of critical parameters which present substantial inter-patient variability. As the number of the involved parameters characterizing both the complex tumour biosystem and possible treatment schemes increases, the resulting exponential increase in computational requirements makes the use of a grid environment for the execution of the simulations a particularly attractive solution. In this paper, a grid-enabled simulation environment for the execution of in silico oncology radiotherapy simulations on grid infrastructures is presented and implementation details are discussed. The environment provides a web portal as the end-user interface and contains advanced features that facilitate the execution of in silico oncology simulations in grid environments. Special consideration has been given during the development of the environment in order to simplify the maintenance and extension of the application, while additional services for Quality of Service provisioning have been applied. The simulation environment has been employed in order to perform several scenarios of glioblastoma multiforme radiotherapy simulations on the Enabling Grids for E-sciencE (EGEE) grid infrastructure. Indicative simulation results, as well as statistics regarding execution times on the grid, are presented.