Regularized tensor factorization for multi-modality medical image classification

  • Authors:
  • Nematollah Batmanghelich;Aoyan Dong;Ben Taskar;Christos Davatzikos

  • Affiliations:
  • Section for Biomedical Image Analysis, Philadelphia;Section for Biomedical Image Analysis, Philadelphia;Section for Biomedical Image Analysis, Philadelphia;Section for Biomedical Image Analysis, Philadelphia

  • Venue:
  • MICCAI'11 Proceedings of the 14th international conference on Medical image computing and computer-assisted intervention - Volume Part III
  • Year:
  • 2011

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Abstract

This paper presents a general discriminative dimensionality reduction framework for multi-modal image-based classification in medical imaging datasets. The major goal is to use all modalities simultaneously to transform very high dimensional image to a lower dimensional representation in a discriminative way. In addition to being discriminative, the proposed approach has the advantage of being clinically interpretable. We propose a framework based on regularized tensor decomposition. We show that different variants of tensor factorization imply various hypothesis about data. Inspired by the idea of multiview dimensionality reduction in machine learning community, two different kinds of tensor decomposition and their implications are presented. We have validated our method on a multi-modal longitudinal brain imaging study. We compared this method with a publically available classification software based on SVM that has shown state-of-the-art classification rate in number of publications.